ea0063oc9.3 | Thyroid 2 | ECE2019
Nieto Hannah
, Thornton Caitlin
, Fletcher Alice
, de Menezes Albert Nobre
, Baker Kate
, Alshahrani Mohammed
, Read Martin
, Boelaert Kristien
, Smith Vicki
, Baptiste Cazier Jean
, Mehanna Hisham
, McCabe Chris
The incidence of thyroid cancer is rapidly increasing worldwide. Whilst outcome in thyroid cancer is generally good, up to 25% of patients develop recurrence, and have a significantly reduced life expectancy. We hypothesise those thyroid tumours which subsequently recur display a distinct pattern of driver events. Whole exome sequencing data were downloaded from The Cancer Genome Atlas (TCGA). Bioinformatic analysis of data on N=43 patients whose tumours recurred was ...